Fig 1: Expression of uridylated RNA degrading enzymes (Dis3L2 and Eri1) and terminal uridyl transferases (TUT4 y TUT7) upon CD4+ T cell activationWestern blot analysis of protein expression in human primary CD4+ T cells from 8 donors stimulated with αCD3αCD28, assessing Dis3L2 (A), Eri1 (B), TUT4 (C) and TUT7 (D). Fold increase compared to non-stimulation was represented for each donor, to observe individual expression evolution upon activation (left panel), and using group median and interquartile range with whiskers ranging from minimum to maximum values (middle panel). Right panels include two examples of different donors for each protein to highlight inter-donor variability in upregulation kinetics. Band intensities were normalized to ERMs values and relativized to unstimulated conditions. Statistical analysis: Kruskal-Wallis test, Dunn's multiple comparisons test [ ∗ p value <0.05, ∗∗ p value<0.01, ∗∗∗ p value<0.001; 0.05